Presently the University the of Karachi consists of eight faculties namely, Arts & Commerce, Science, Pharmacy, Education, Medicine, Law, and Islamic Studies. Forty-three departments function under these faculties on the campus. Apart from these, there are 17 research centers of excellence and 97 affiliated colleges. The University offers honors and postgraduate courses besides research programs leading to M.PhiL  and Ph.D degrees. nearly 13,000 students, out of which 4% are foreign students are enrolled in the university.

Teaching and research is conducted by highly qualified teachers, some of whom have been internationally acclaimed. Nineteen departments of the faculty of Arts and commerce offer honors and masters level courses and research facilities leading to M.PhiL and Ph.D degrees. The faculty of Arts & Commerce also offers certificate courses in Arabic, English, Persian, Hindi, Sindhi, Spanish, French, Turkish, German, and Urdu for foreigners. Other subjects in which diplomas are offered offered are Persian, Sindhi, Local Government, Public, Administration, Economics, Finance and Transport.

Over the past seven years, over 200 Ph.D and around 185 M.PhiL degrees have been awarded in various disciplines in the faculties of Arts, Commerce, Pharmacy and Science.

The University of Karachi is on the move; it is constantly striving to update and expand academic facilities offered in various disciplines. Several departments are successfully forging academic linkages with reputed universities and college at home and abroad. The university of Karachi is geared to meet the human resource development needs of the country in the new millennium.